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|
Variable
|
DFS
|
|---|
|
Univariate analysis
|
Multivariate analysis
|
|---|
|
P value
|
HR (95% CI)
|
P value
|
HR (95% CI)
|
|---|
|
Age (yr)
|
0.369
|
0.722 (0.355–1.470)
| | |
|
≤ 50 vs > 50
|
|
Gender
|
0.784
|
1.092 (0.581–2.054)
| | |
|
Male vs female
|
|
Tumor diameter (cm)
|
0.001**
|
2.999 (1.612–5.577)
|
0.228
|
1.536 (0.765–3.086)
|
|
≤ 4 vs > 4
|
|
Tumor location
|
0.693
|
0.877 (0.457–1.681)
| | |
|
Up + Middle vs Down
|
|
Tumor differentiation
|
0.043*
|
1.895 (1.021–3.515)
|
0.353
|
1.361 (0.710–2.610)
|
|
High + Middle vs Low
|
|
CEA (ng/ml)
|
0.135
|
1.755 (0.839–3.672)
| | |
|
≤ 5 vs > 5
|
|
CA 19-9 (U/ml)
|
0.845
|
0.926 (0.429–2.000)
| | |
|
≤ 37 vs > 37
|
|
HP infection
|
0.746
|
0.905 (0.494–1.658)
| | |
|
− vs +
|
|
T stage
|
0.002**
|
3.270 (1.561–6.849)
|
0.724
|
0.842 (0.325–2.184)
|
|
T1-2 vs T3-4
|
|
N stage
|
< 0.0001****
|
7.548 (3.324–17.140)
|
0.017*
|
3.188 (1.235–8.230)
|
|
N0 vs N1-3
|
|
HOXA-AS3 in tissues
|
< 0.0001****
|
7.462 (3.420–16.283)
|
0.005**
|
4.014 (1.534–10.508)
|
|
High vs Low
|
- *P < 0.05; **P < 0.01; ****P < 0.0001
